Hirokazu Tsukahara Selected Research

progressive familial intrahepatic 1 Cholestasis

1/2009	Effects of bezafibrate on dyslipidemia with cholestasis in children with familial intrahepatic cholestasis-1 deficiency manifesting progressive familial intrahepatic cholestasis.
7/2007	Depletion of high-density lipoprotein and appearance of triglyceride-rich low-density lipoprotein in a Japanese patient with FIC1 deficiency manifesting benign recurrent intrahepatic cholestasis.

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Hirokazu Tsukahara Research Topics

Disease

9	Brain Diseases (Brain Disorder) 01/2022 - 02/2012
7	Infections 12/2021 - 01/2013
5	Pneumonia (Pneumonitis) 01/2019 - 01/2013
4	Human Influenza (Influenza) 12/2021 - 01/2013
4	Hypercholesterolemia 01/2018 - 07/2007
4	Cholestasis 06/2010 - 07/2007
3	Fatty Liver 05/2022 - 11/2012
3	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 04/2022 - 02/2004
3	Seizures (Absence Seizure) 01/2019 - 02/2014
3	Encephalitis (Encephalitis, Rasmussen) 01/2019 - 08/2013
3	Neonatal-onset citrullinemia type 2 01/2019 - 05/2009
3	Liver Diseases (Liver Disease) 01/2019 - 10/2006
3	Phenylketonurias (Phenylketonuria) 06/2014 - 07/2011
3	Hepatolenticular Degeneration (Wilson's Disease) 11/2012 - 10/2006
3	Atopic Dermatitis (Atopic Eczema) 01/2007 - 04/2003
2	Airway Remodeling 01/2022 - 10/2007
2	Hypoglycemia (Reactive Hypoglycemia) 01/2022 - 06/2011
2	Inflammation (Inflammations) 11/2021 - 11/2012
2	Acute Lung Injury 01/2019 - 01/2013
2	Leukemia 08/2018 - 11/2017
2	Ornithine Carbamoyltransferase Deficiency Disease 07/2013 - 03/2009
2	Citrullinemia 05/2009 - 03/2009
2	Dyslipidemias (Dyslipidemia) 01/2009 - 06/2008
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2009 - 10/2006
2	progressive familial intrahepatic 1 Cholestasis 01/2009 - 07/2007
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2009 - 10/2006
2	Lung Diseases (Lung Disease) 10/2007 - 01/2004
2	Diabetes Mellitus 01/2007 - 05/2005
2	Skin Diseases (Skin Disease) 07/2004 - 05/2004
1	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 02/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Light Fixation Seizure Syndrome 01/2022
1	Disease Progression 01/2022
1	Acro-Osteolysis (Acroosteolysis) 01/2022
1	Paraplegia (Spastic Paraplegia) 01/2022
1	Hyperlipidemias (Hyperlipidemia) 01/2022
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2021
1	Neonatal Abstinence Syndrome 10/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 09/2021
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 08/2021
1	Eosinophilia 08/2021
1	Acute Kidney Injury (Acute Renal Failure) 12/2020
1	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2020
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2020
1	Drug Resistant Epilepsy 05/2020
1	Otitis Media 01/2020

Drug/Important Bio-Agent (IBA)

7	AntioxidantsIBA 11/2012 - 10/2002
6	Biomarkers (Surrogate Marker)IBA 09/2021 - 01/2007
5	Proteins (Proteins, Gene)FDA Link 05/2022 - 05/2006
5	HMGB1 Protein (HMG1)IBA 04/2022 - 06/2015
5	Oxidants (Oxidizing Agents)IBA 09/2021 - 10/2002
5	Urea (Carbamide)FDA LinkGeneric 01/2019 - 03/2009
4	ThioredoxinsIBA 05/2022 - 01/2013
4	Lysine (L-Lysine)FDA Link 01/2011 - 10/2002
4	Acrolein (Aqualin)IBA 01/2011 - 10/2002
4	pentosidineIBA 01/2007 - 09/2003
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2004 - 10/2002
3	SteroidsIBA 02/2022 - 10/2002
3	CreatinineIBA 02/2022 - 09/2003
3	Monoclonal AntibodiesIBA 01/2019 - 06/2015
3	CalciumIBA 01/2016 - 06/2002
3	CopperIBA 11/2012 - 10/2006
3	NitritesIBA 03/2009 - 10/2002
3	Lipoproteins (Lipoprotein)IBA 01/2009 - 07/2007
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2021 - 10/2002
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 02/2005
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 07/2007
2	C-Reactive ProteinIBA 01/2020 - 01/2018
2	Immunoglobulin G (IgG)IBA 10/2019 - 01/2012
2	ProcalcitoninIBA 01/2019 - 01/2018
2	CarbohydratesIBA 01/2019 - 06/2011
2	citrinIBA 01/2019 - 01/2018
2	CytokinesIBA 01/2018 - 01/2017
2	CholesterolIBA 01/2018 - 07/2017
2	Messenger RNA (mRNA)IBA 01/2018 - 01/2017
2	Vitamin D FDA LinkGeneric 01/2016 - 02/2013
2	Arginine (L-Arginine)FDA Link 07/2013 - 03/2009
2	EnzymesIBA 11/2012 - 05/2005
2	Cholesterol Ester Transfer ProteinsIBA 08/2009 - 07/2007
2	NitratesIBA 03/2009 - 01/2007
2	Free RadicalsIBA 01/2009 - 10/2006
2	oxidized low density lipoproteinIBA 03/2008 - 07/2007
2	HDL LipoproteinsIBA 03/2008 - 07/2007
2	8-Hydroxy-2'-DeoxyguanosineIBA 01/2007 - 09/2003
1	histidine-rich proteinsIBA 04/2022
1	Omalizumab (Xolair)FDA Link 01/2022
1	IFIH1 Interferon-Induced HelicaseIBA 01/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2021
1	Environmental Pollutants (Pollutants, Environmental)IBA 11/2021
1	AllergensIBA 11/2021
1	nasIBA 10/2021
1	A-factor (Streptomyces)IBA 08/2021
1	Tacrolimus (Prograf)FDA LinkGeneric 12/2020
1	Methotrexate (Mexate)FDA LinkGeneric 12/2020
1	Adrenocorticotropic Hormone (ACTH)FDA Link 05/2020
1	pazopanib FDA Link 01/2020

Therapy/Procedure

9	Therapeutics 01/2022 - 01/2009
2	Stents 08/2019 - 02/2005
2	Drug Therapy (Chemotherapy) 08/2018 - 03/2017
2	Hematopoietic Stem Cell Transplantation 03/2017 - 06/2016